PI(s): Boly & Momany
Primary Team Members: Gretchen Larson
IRB: NICU Umbrella IRB
Funding: N/A
Status: Chart review
Study Design: Retrospective cohort; preterm infants hospitalized in UIHC NICU split into 2 cohorts: before and after regular probiotic use in NICU. Data on growth and neurodevelopment collected via chart abstraction from birth to 24 months corrected age.
Description: The administration of probiotics in the neonatal period has been routinely performed as a measure to decrease intestinal dysbiosis and reduce the incidence of necrotizing enterocolitis. Based on the outcomes of extremely premature infants at the University of low we would like to compare outcome data for this group of infants in the time prior to and following routine administration of probiotics. Our hypothesis is infants who received probiotics will have improved growth (weight, length, and head circumference) at the time of discharge and will have improved neurodevelopmental outcomes, as assessed by the Bayley Scales of Infant and Toddler Development, performed at or near 24 months of age.

PI(s): Boly & Momany

Primary Team Members: Gretchen Larson

IRB: NICU Umbrella IRB

Funding: N/A

Status: Chart review

Study Design: Retrospective cohort; preterm infants hospitalized in UIHC NICU split into 2 cohorts: before and after regular probiotic use in NICU. Data on growth and neurodevelopment collected via chart abstraction from birth to 24 months corrected age.

Description: The administration of probiotics in the neonatal period has been routinely performed as a measure to decrease intestinal dysbiosis and reduce the incidence of necrotizing enterocolitis. Based on the outcomes of extremely premature infants at the University of low we would like to compare outcome data for this group of infants in the time prior to and following routine administration of probiotics. Our hypothesis is infants who received probiotics will have improved growth (weight, length, and head circumference) at the time of discharge and will have improved neurodevelopmental outcomes, as assessed by the Bayley Scales of Infant and Toddler Development, performed at or near 24 months of age.